MSM (The Elasticity Factor)
Also Known As: Methylsulfonylmethane, Organic Sulfur, Dimethyl Sulfone
Compound Type: Organic Sulfur Compound / Anti-Inflammatory
If Vitamin C is the “brick” of penis enlargement, MSM is the “mortar.” Sulfur is the fourth most abundant mineral in the human body and is absolutely critical for the formation of healthy connective tissue.
In the context of PE, MSM solves the biggest problem men face: Tissue Hardening. As you stress the penis, it heals. If it heals with rigid scar tissue (fibrosis), your gains stop. MSM ensures that new cells remain flexible, permeable, and elastic, allowing for continuous expansion.
How Does MSM Increase Penis Size?
MSM modifies how collagen bonds form during the healing process, ensuring the Tunica Albuginea stays stretchy rather than becoming brittle.
The Science: Disulfide Bonds & Permeability
1. The “Flexibility” Bond:
Collagen fibers are held together by cross-links. MSM provides the sulfur required to create flexible disulfide bonds. Without adequate sulfur, collagen cross-links become rigid and brittle. Flexible tissue expands; brittle tissue resists growth.
2. Cell Permeability (Nutrient Delivery):
MSM increases the permeability of cell walls. This means it allows excess fluid and toxins (lactic acid) to flow out of the cells, while allowing nutrients (oxygen, zinc, arginine) to flow in. This significantly speeds up recovery between hanging/pumping sessions.
3. Preventing Fibrosis:
Research suggests MSM acts as a natural anti-inflammatory that helps prevent the over-accumulation of scar tissue (fibrosis). This is vital for men using high-tension devices like extenders.
You should almost never take MSM without Vitamin C. They are biologically co-dependent. Vitamin C stimulates the production of collagen, and MSM determines the structure of that collagen. Take 3g of MSM with 1g of Vitamin C daily.
✔ The Verdict: ELASTICITY KING
5/5 Stars. This is a non-negotiable supplement for advanced PE. If your tunica becomes too tough, you hit a “plateau.” MSM keeps the tissue compliant, allowing you to break through plateaus and gain size safely.
2g – 5g
Powder or Pills
Start low to avoid detox symptoms
Safety Profile & Side Effects
- Vivid Dreams: A very common, harmless side effect of sulfur.
- “Detox” Effect: Mild headaches or skin breakouts in the first week as cells dump toxins.
- Blood Thinners: MSM has a mild blood-thinning effect. Consult a doctor if on Warfarin.
- Alcohol: MSM metabolizes alcohol faster (may reduce hangovers, but increases processing load).
Data source: Examine / PubMed


