L-Citrulline (The Superior Vasodilator)
Compound Type: Amino Acid / Nitric Oxide Precursor
Citrulline is an amino acid naturally found in watermelon, originally isolated in 1914. While L-Arginine often gets the spotlight, modern research has confirmed that Citrulline is actually the superior supplement for penis enlargement.
It serves two main functions: eliminating toxic ammonia (waste) from the body and acting as a potent precursor to Nitric Oxide. In the medical community, it is considered the “Gold Standard” for natural erection quality improvement.
Why is Citrulline Better Than Arginine?
This is known as the “Arginine Paradox.” When you take an L-Arginine supplement, it must pass through the liver, where an enzyme called arginase destroys a massive amount of it before it ever reaches your bloodstream.
Citrulline bypasses the liver entirely. It travels to the kidneys, where it is converted directly into L-Arginine and released into the blood. This results in significantly higher sustained plasma Arginine levels than if you had taken Arginine itself.
The Science: Sustained “Pump” & Hardness
1. The “Time-Release” Effect:
Because Citrulline must be converted in the kidneys, it acts like a natural time-release mechanism. This prevents the “crash” often associated with pre-workout supplements and keeps blood levels elevated for hours, ensuring better nocturnal erections (which are crucial for tissue growth).
2. Ammonia Scavenging:
Penis enlargement exercises (stretching/jelqing) can cause cellular fatigue. Citrulline helps clear metabolic waste (ammonia/lactate), allowing for faster recovery between sessions.
3. Viagra-Like Properties:
While not a PDE5 inhibitor like Viagra, Citrulline achieves a similar goal via a different pathway. By maximizing endothelial Nitric Oxide saturation, it lowers the threshold for arousal, meaning it takes less physical stimulation to achieve 100% rigidity.
✔ The Verdict: GOLD STANDARD
The #1 Recommendation. If you can only afford one supplement for Penis Enlargement, make it Citrulline. It provides the raw fuel needed for expansion without the absorption issues of L-Arginine. It pairs perfectly with pumping and clamping routines.
3g – 6g
Pre-Workout / Daily
Higher than Arginine
Safety Profile & Side Effects
- Mild stomach discomfort (rare, unlike Arginine).
- Safe Profile: Citrulline is generally much better tolerated than Arginine, which often causes diarrhea at high doses.
- PDE5 Inhibitors: Viagra/Cialis. Citrulline may increase the potency of these drugs, potentially causing hypotension. Monitor blood pressure.
Data source: WebMD / NCBI


